RESEARCH PUBLICATIONS
Le Guen Y, Belloy ME, Grenier-Boley B, de Rojas I, Castillo-Morales A, Jansen I, Nicolas A, Bellenguez C, Dalmasso C, Küçükali F, Eger S, Rasmussen KL, Thomassen JQ, Deleuze JF, He Z, Napolioni V, Amouyel P, Jessen F, Kehoe PG, van Duijn C, Tsolaki M, Sánchez-Juan P, Sleegers K, Ingelsson M, Rossi G, Hiltunen M, Sims R, van der Flier WM, Ramirez A, Andreassen OA, Frikke-Schmidt R, Williams J, Ruiz A, Lambert JC, Greicius MD: Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease (2022).
Belloy ME, Eger SJ, Le Guen Y, Damotte V, Ahmad S, Ikram MA, Ramirez A, Tsolaki AC, Rossi G, Jansen IE, de Rojas I, Parveen K, Sleegers K, Ingelsson M, Hitunen M, Andreassen O, Sánchez-Juan P, Kehoe P, Amouyel P, Sims R, Frikke-Schmidt R, van der Flier WM, Lambert JC, He Z, Han SS, Napolioni V, Greicius MD: Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping (2022)
Eger SJ, Le Guen Y, Khan RR, Hall JN, Kennedy G, Zaharchuk G, Couthouis J, Brooks WS, Velakoulis D, Napolioni V, Belloy ME, Dalgard CL, Mormino EC, Gitler AD, Greicius MD: Confirming Pathogenicity of the F386L PSEN1 Variant in a South Asian Family With Early-Onset Alzheimer Disease (2022)
He Z, Le Guen Y, Liu L, Lee J, Ma S, Yang AC, Liu X, Rutledge J, Losada PM, Song B, Belloy ME, Butler III RR, Longo FM, Tang H, Mormino EC, Wyss-Coray T, Greicius MD, Ionita-Laza I: Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics (2021).
Le Guen Y, Belloy ME, Napolioni V, Eger SJ, Kennedy G, Tao R, He Z, Greicius MD: A novel age-informed approach for genetic association analysis in Alzheimer’s disease. Alzheimer's Research Therapy (2021).
Sanyak N, Napolioni V, de Rochemonteix M, Belloy ME, Caporaso NE, Landi MT, Greicius MD, Chatterjee N, Han SS: A Robust Test for Additive Gene-Environment Interaction Under the Trend Effect of Genotype Using an Empirical Bayes-Type Shrinkage Esimator (2021)
Le Guen Y, Napolioni V, Belloy ME, Yu E, Krohn L, Ruskey JA, Gan-Or Z, Kennedy G, Eger SJ, Greicius MD: Common X-chromosome variants are associated with Parkinson’s disease risk. Annals of Neurology (2021).
Belloy ME, Eger SJ, Le Guen Y, Napolioni V, Deters KD, Yang H-S, Scelsi MA, Porter T, James S-N, Wong A, Schott JM, Sperling RA, Laws SM, Mormino EC, He Z, Han SS, Altmann A, Greicius MD: KL*VS heterozygosity reduces brain amyloid in asymptomatic at risk APOE*4 carriers. Neurobiology of Aging (2021)
Napolioni V, Scelsi MA, Khan RR, Altmann A, Greicius MD: Recent consanguinity and outbred autozygosity are associated with increased risk of late-onset Alzheimer’s disease. Frontiers in Genetics (2021).
Belloy ME, Napolioni V, Han SS, Le Guen Y, Greicius MD: Klotho-VS heterozygosity reduces risk for Alzheimer’s disease in APOE4 carriers. JAMA Neurology (2020).
Christopher L, Napolioni V, Khan RR, Han S, and Greicius MD: A variant in PPP4R3A protects against alzheimer-related metabolic decline. Annals of Neurology (2018).
Dresler M, Shirer WR, Konrad BN, Muller NCJ, Wagner IC, Fernandez G, Czisch M, and Greicius MD: Mnemonic Training Reshapes Brain Networks to Support Superior Memory. Neuron (2017).
Richiardi J, Altmann A, Milazzo AC, Chang C, Chakravarty MM, Banaschewski T, Barker G, Bokde A, Bromberg U, Buechel C, Conrod P, Fauth-Buehler M, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Lemaitre H, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Robbins T, Smolka M, Spanagel R, Stroehle A, Schumann G, Hawrylycz M, Poline JB, Greicius MD, and The IMAGEN consortium: Correlated gene expression supports synchronous activity in brain networks. Science (2015).
Altmann A, Tian L, Hnderson V, Greicius MD: Sex Modifies the APOE-Related Risk of Developing Alzheimer Disease. Annals of Neurology (2014).
Parvizi J, Rangarajan V, Shirer WR, Desai N, Greicius MD: The Will to Persevere Induced by Electrical Stimulation of the Human Cingulate Gyrus. Neuron (2013).
Hall S, Jiang H, Reiss A, Greicius MD: Identifying Large-scale Brain Networks in Fragile X Syndrome. Arch Gen Psychiatry (2013).
Lehmann M, Ghosh PM, Madison C, Laforce R Jr, Corbetta-Rastelli C, Weiner MW, Greicius MD, Seeley WW, Gorno-Tempini ML, Rosen HJ, Miller BL, Jagust WJ, Rabinovici GD: Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease. Brain (2013).
Greicius MD, Kimmel DL: Neuroimaging insights into network-based neurodegeneration. Curr Opin Neurol (2012).
Greicius MD, Seeley WW: Introduction to the special issue on connectivity. Neuroimage (2012).
Damoiseaux JS, Seeley WW, Zhou J, Shirer WR, Coppola G, Karydas A, Rosen HJ, Miller BL, Kramer JH, Greicius MD; Alzheimer's Disease Neuroimaging Initiative: Gender modulates the APOE E4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels. J Neurosci (2012).
Fox MD, Buckner RL, White MP, Greicius MD, Pascual-Leone A: Efficacy of transcranial magnetic stimulation targets for depression is related to intrinsic functional connectivity with the subgenual cingulate. Biol Psychiatry (2012).
Damoiseaux JS, Prater KE, Miller BL, Greicius MD: Functional connectivity tracks clinical deterioration in Alzheimer's disease. Neurobiol Aging (2012).
Shirer WR, Ryali S, Rykhlevskaia E, Menon V, Greicius MD: Decoding subject-driven cognitive states with whole-brain connectivity patterns. Cereb Cortex (2012).
Mormino EC, Smiljic A, Hayenga AO, Onami S, Greicius MD, Rabinovici GD, Janabi M, Baker SL, Yen I, Madison CM, Miller BL, Jagust WJ: Relationships between beta-amyloid and functional connectivity in different components of the default mode network in aging. Cereb Cortex (2011).
Dastjerdi M, Foster BL, Nasrullah S, Rauschecker AM, Dougherty RF, Townsend J, Chang C, Greicius MD, Menon V, Kennedy D, Parvizi J: Differential electrophysiological response during rest, self-referential and non-self-referential tasks in human posteromedial cortex. Proc Natl Acad Sci (2011).
Supekar K, Uddin LQ, Prater K, Amin H, Greicius MD, Menon V: Development of functional and structural connectivity within the default mode network in young children. Neuroimage (2010).
Zhou J, Greicius MD, Gennatas S, Growdon ME, Jang JY, Kramer JH, Weiner M, Miller BL Seeley WW: Divergent network connectivity changes in behavioral variant FTD and Alzheimer's disease. Brain (2010).
Uddin L, Supekar K, Hitha A, Rykhlevskaia E, Nguyen D, Greicius MD, Menon V: Dissociable connectivity within human angular gyrus and intraparietal sulcus: Evidence from functional and structural connectivity. Cereb Cortex (2010).
Vanhaudenhuyse A, Noirhomme Q, Tshibanda L, Bruno MA, Boveroux P, Schnakers C, Soddu A, Perlbarg V, Ledoux D, Brichant JF, Moonen G, Maquet P, Greicius MD, Laureys S, Boly M: Default network connectivity reflects the level of consciousness in non-communicative brain damaged patients. Brain 133:161-71 (2010).
Gonella MC, Fischbein NJ, Lane B, Shuer LM, Greicius MD: Episodic encephalopathy due to an occult spinal vascular malformation complicated by superficial siderosis. Clin Neurol Neurosurg 112(1):82-4 (2010).
Habas C, Kamdar N, Nguyen D, Prater KE, Beckmann CF, Menon V, Greicius MD: Distinct cerebellar contributions to intrinsic connectivity networks. J Neurosci 29:8586-94 (2009).
Etkin A, Keller KE, Schatzberg AF, Menon V, Greicius MD: Disrupted amygdalar subregion functional connectivity and evidence for a compensatory network in generalized anxiety disorder. Arch Gen Psychiatry 66(12):1361-72 (2009).
Seeley WW, Crawford RK, Zhou J, Miller BL, Greicius MD: Human neurodegenerative syndromes target intrinsic functional brain networks. Neuron 2009 Apr 16;62(1):42-52.
Supekar K, Menon V, Ruben DL, Musen MA, Greicius MD: Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. PLoS Comput Biol 4:e1000100 (2008).
Greicius MD, Supekar K, Menon V, Dougherty RF: Resting-state functional connectivity reflects structural connectivity in the default-mode network. Cereb Cortex 19:72-8 (Epub 2008).
Thomason ME, Chang CE, Glover GH, Gabrieli JDE, Greicius MD, Gotlib IH: Default-mode function and task-induced deactivation have overlapping brain substrates in children. Neuroimage 41:1493-1503 (2008).
Eckert MA, Kamdar NV, Chang CE, Greicius MD, Menon V: Seeing with your eyes closed: A crossmodal system linking auditory and visual cortex. Hum Brain Mapp 29:848-57 (2008).
Greicius MD, Kiviniemi V, Tervonen O, Vainionpää V, Alahuhta S, Reiss AL, Menon V: Persistent default-mode network connectivity during light sedation. Hum Brain Mapp 29:839-847 (2008).
Greicius MD, Flores BH, Menon V, Glover GH, Solvason HB, Kenna H, Reiss AL, Schatzberg AF: Resting-state functional connectivity in major depression: Abnormally increased contributions from subgenual cingulate cortex and thalamus. Biol Psychiatry 62:429-37 (2007).
Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD: Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 27:2349-56 (2007).
Karnik NS, D'Apuzzo M, Greicius MD: Non-fluent progressive aphasia, depression and OCD in a woman with progressive supranuclear palsy: Neuroanatomical and neuropathological correlations. Neurocase 12:332-8 (2006).
Greicius MD and Menon, V: Default-mode activity during a passive sensory task: Uncoupled from deactivation but impacting activation. J Cogn Neurosci 16:1484-92 (2004).
Greicius MD, Boyett-Anderson JM, Menon V, Reiss AL: Reduced basal forebrain and hippocampal activation during memory encoding in girls with fragile X syndrome. NeuroReport 15:1579-83 (2004).
Greicius MD, Srivastava S, Reiss AL, Menon V: Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from fMRI. Proc Natl Acad Sci 101:4637-42 (2004).
Alireza A, Sherman S, Norman KA, Kirchhoff BA, Nicolas MM, Greicius MD, Cramer SC, Breiter HC, Hasselmo ME, Stern CE: Blockade of central cholinergic receptors impairs new learning and increases proactive interference in a word paired-associate memory task. Beh Neurosci 118:223-36 (2004).
Mobbs D, Greicius MD, Abdel-Azim E, Menon V, Reiss AL: Humor modulates the mesolimbic reward centers. Neuron 40:1041-8 (2003).
Krasnow B, Tamm L, Greicius MD, Yang TT, Glover GH, Reiss AL, Menon V: Comparison of fMRI activation at 1.5 T and 3T during perceptual, cognitive and affective processing. Neuroimage 18:813-26 (2003).
Greicius MD, Krasnow B, Reiss AL, Menon V: Functional connectivity in the resting brain: A network analysis of the default mode hypothesis. Proc Natl Acad Sci 100:253-258 (2003).
Greicius MD, Krasnow B, Boyett-Anderson JM, Eliez S, Schatzberg AF, Reiss AL, Menon V: Regional analysis of hippocampal activation during encoding and retrieval: An fMRI study. Hippocampus 13:164-174 (2003).
REVIEWS, CHAPTERS, INVITED PAPERS
Belloy ME, Napolioni V, and Greicius MD: A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward. Neuron (2019).
Greicius MD, Geschwind M, Miller BL: Presenile dementia syndromes: An update on taxonomy and diagnosis. J Neurol Neurosur Psychiatry 72:691-700 (2002).
Miller BL, Rosen HJ, Greicius MD: Frontotemporal dementia. In: Asbury AK, McKhann GM, McDonald WI, Goadsby PJ, McArthur JC (eds.) Diseases of the Nervous System: Clinical Neuroscience and Therapeutic Principles, 3rd edition. Cambridge University Press, Cambridge (2002).
Greicius MD, Rosen HJ, Miller BL: Alzheimer's disease. In: Aminoff, M, Daroff, R (eds.) The Encyclopedia of the Neurological Sciences,Vol. I. Academic Press, San Diego (2003).
Greicius MD: Neuroimaging in developmental disorders. Curr Opin Neurol 16:143-146 (2003).
Illes J, Rosen A, Greicius MD, Racine E: Prospects for prediction: An ethics analysis of neuroimaging in Alzheimer's disease. Ann N Y Acad Sci 1097: 278-295 (2007).
Seeley WW, Allman JM, Carlin DA, Crawford RK, Macedo MN, Greicius MD, DeArmond SJ, Miller BJ: Divergent social functioning in frontotemporal dementia and Alzheimer's disease: reciprocal networks and neuronal evolution. Alzheimer Dis Assoc Disord 21:S50-57 (2007).
Greicius MD: Resting-state functional connectivity in neuropsychiatric disorders. Curr Opin Neurol 24:424-430 (2008).
Damoiseaux JS, Greicius, MD: Greater than the sum of its parts: A review of studies combining structural connectivity and resting-state functional connectivity. Brain Struct Funct 213(6):525-33 (2009).